What is the significance of detecting bacteria and WBC count in the third glass of a three-glass specimen?

Detecting bacteria and an elevated white blood cell (WBC) count in the third glass of a three-glass specimen is significant as it points to a prostatic infection, often referred to as prostatitis. In a three-glass urine test, each glass represents a different stage of urine collection: the first glass contains urine from the beginning of urination (representing the urethra), the second glass captures midstream urine (representing the bladder), and the third glass consists of the final portion of urine that may reflect the condition of the prostate.

When bacteria and white blood cells are present in the third glass, it suggests that the prostate is involved, as this is the last part of the urine that is expelled, which is most likely to carry any infection present in the prostate gland. Elevated WBCs indicate inflammation or infection, further supporting the likelihood of prostatitis. Thus, the presence of these findings specifically in the third glass leads to the conclusion that the prostate is affected.

This interpretation is crucial in clinical diagnostics, as it allows healthcare providers to determine the appropriate management and treatment plan tailored to the patient's specific urinary and prostate health issues.